Palo Alto Investors

Palo Alto Dissatisfied with AMAG Performance

November 22, 2010 Board of DirectorsAMAG Pharmaceuticals, Inc.100 Hayden AvenueLexington, MA 02421 Members of the Board: As you know, Palo Alto Investors, LLC (“Palo Alto Investors”), together with its affiliates, is one of the largest stockholders of AMAG Pharmaceuticals, Inc. (“AMAG” or the “Company”), holding an ownership stake of approximately 9.3% of the Company’s outstanding…

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